Toxicity of vancomycin on corneal endothelium in rabbits

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[Mitomycin C toxicity in rabbit corneal endothelium].

PURPOSE To evaluate corneal endothelium alterations after applying mitomycin C to the sclera using transmission and scanning electron microscopy, correlating alterations with time, concentration, and evaluation methods. METHODS The corneal endothelium of both eyes of 32 albino rabbits was evaluated and distributed into four groups of 8. Mitomycin C was applied under a scleral flap in the righ...

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P 190 Corneal endothelial toxicity of mitomycin C in rabbits

Hsldw S.A.1, Buh~r~~nly J.1, Haswll P.D.1, Bowbr I.C.J.W.2, Bmn A.J.1 1 Depatlmenl of Ophthalmology, University ot Oxford. 2 Department of Bacterioboy. Oxford Regional FMii Heaith Laboratory. Purpose: lntravitreal antibiotic is the mainstay of endophthalmitis treatment. Repeat injections should be based on the knowledege of tissue levels. The purpose of this study is to assess the value of aque...

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Effect of Different Treatment Regimen with Dexamethasone and Acetylcysteine on Corneal Wound Healing in Rabbits

Background: The effect of corticosteroid therapy on corneal wound healing is controversial. The objective of this study was to evaluate the effects of combination therapy with dexametha-sone and acetylcysteine at different times and durations on experimentally-induced corneal wounds and haze in rabbits. Methods: Eighteen adult New Zealand white rabbits were divided into three groups of ...

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Influence of dorzolamide on corneal endothelium.

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Effect of carbachol on rabbit corneal endothelium.

We investigated the current reformulation of the commercially available intraocular preparation of carbachol for its effect on corneal thickness and endothelial cell ultrastructure. A 15-minute perfusion in the specular microscope with 0.01% carbachol caused a significant increase in the corneal swelling rate, which returned to control values after 75 minutes of reperfusion with Krebs Ringer bi...

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ژورنال

عنوان ژورنال: Acta Ophthalmologica Scandinavica

سال: 1998

ISSN: 1395-3907

DOI: 10.1034/j.1600-0420.1998.760608.x